Serum antibody response to polysaccharides in children with recurrent respiratory tract infections.

نویسندگان

  • A López-Yap
  • A Abdelnour
  • B Lomonte
  • O Porras
چکیده

We evaluated children (15-months old and older) with recurrent upper respiratory tract infections and normal levels of immunoglobulins in serum for specific polysaccharide immunodeficiency using an enzyme-linked immunosorbent assay method. Results showed that of 12 patients vaccinated with Act-HIB vaccine, one did not develop specific antibodies to Haemophilus influenzae type b, demonstrating that such immunodeficiency is present in Costa Rican children.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Selective Antibody Deficiency and its Relation to the IgG2 and IgG3 Subclass Titers in Recurrent Respiratory Infections

Background: Selective antibody deficiency with normal immunoglobulins (SADNI) may be identified as part of distinct primary or secondary immunodeficiency disorders. The clinical manifestations include recurrent, often severe or prolonged, upper or lower respiratory tract infections. Objectives: To evaluate SADNI in patients with recurrent sinopulmonary infections and its relation to IgG subclas...

متن کامل

سطح سرمی ویتامین‌های A، D و روی در کودکان شش ماه تا پنج سال مبتلا و غیرمبتلا به عفونت تنفسی

Background: Severity of respiratory infection in children is depended on various fac-tors such as causative organism and the host immunologic response to the organism. Vitamins and micronutrients play an important role in this response with supporting the immune system and therefore, the response to infections. Nutritional deprivations in children, especially vitamins and micronutrients such as...

متن کامل

P13 - Vaccination against Haemophilus B as a treatment of recurrent upper respiratory tract infections

Haemophilus influenza b (Hib) conjugate vaccines are highly immunogenic in infants, as >95% develop protective antibody levels after 2 or 3 doses; hence invasive Hib disease is now uncommon in vaccinated children. The precise protective level is not clearly established, although a titre of 1 μg/mL is considered to offer longterm protection. Hib vaccination above the age of 5 is not recommended;...

متن کامل

Response to pneumococcal polysaccharide vaccine in children with asthma, and children with recurrent respiratory infections, and healthy children.

BACKGROUND To analyse specific immune response to the 23-valent pneumococcal polysaccharide vaccine by measuring pneumococcal antibodies in children with asthma and with respiratory recurrent infection (RRI) as compared to healthy children. METHODS The study included 60 children, divided into three groups: 20 with asthma, 20 with RRI, and 20 healthy controls. Post-vaccination specific IgG ant...

متن کامل

تعیین فراوانی عفونت ویروسی پاراآنفلوآنزا به روش ایمونوفلوئورسانس در عفونت‌های حاد تنفسی

Background: Acute respiratory tract infections, both bacterial and viral, cause 4.5 million childhood deaths worldwide, most of which occur in developing countries. Parainfluenza viruses, of the paramyxoviridae family, are among the common causes of acute respiratory infections, giving rise to 30% of respiratory infections in children before school age. The four parainfluenza viruses that cause...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Clinical and diagnostic laboratory immunology

دوره 8 5  شماره 

صفحات  -

تاریخ انتشار 2001